MT-2 and PT-141 are usually listed as separate products, but the literature tells one connected story: PT-141 is a metabolite of MT-2, and both are cyclic analogs of the same natural hormone. Understanding one means understanding the pair.
The shared backbone
Both compounds are synthetic cyclic analogs of alpha-melanocyte-stimulating hormone (alpha-MSH), the endogenous peptide that signals through the melanocortin receptor family. MT-2 (Melanotan II) came first, described in the early melanocortin literature as a potent, non-selective agonist across melanocortin receptors. PT-141 (bremelanotide) was subsequently characterized as an active metabolite of MT-2 and became a research focus in its own right.
Where each stands
Their paths split sharply on regulatory status. A pharmaceutical form of bremelanotide is an approved drug, developed through published clinical programs, which gives PT-141 a documented human pharmacology record. MT-2, by contrast, was investigated but never approved anywhere, and the published literature on it includes explicit safety discussions about its unregulated circulation. We state that plainly because honesty about the record is the whole brand.
What laboratories study
Published melanocortin work spans receptor subtype selectivity (MC1R through MC5R), signaling downstream of receptor activation, and structure-activity relationships across alpha-MSH analogs, where MT-2 and PT-141 are standard reference compounds. As with everything here: research-grade material is not a pharmaceutical product.
In our catalog
We stock MT-2 (10mg) and PT-141 (10mg) as lyophilized research compounds, each with specifications on its product page and a printed lot number tied to our public COA ledger. Lots awaiting certification are labeled pending.
Quick answers
Are MT-2 and PT-141 the same thing? No, but they are directly related: PT-141 is described in the literature as an active metabolite of MT-2, with different receptor selectivity and a very different regulatory history.
Is either an approved drug? A pharmaceutical form of bremelanotide (PT-141) is; MT-2 never was. Research-grade material of either is not a pharmaceutical product.
How do I verify a lot? Match the label's lot number to its ledger entry.
For laboratory and in-vitro research use only.
For laboratory and in-vitro research use only. Not for human or veterinary use. See our research-use disclaimer.
